Thursday, April 23, 2015

Mortality in Lupus Patients Does Not Differ By Dialysis Type

Lupus affects mainly the joints, kidneys and skin.  It can affect the skin, joints, kidneys, lungs, nervous system and other organs of the body. These symptoms vary over time in intensity and duration for each patient as well as from patient to patient. Many of these interventions can be modified for the hospitalized patient.

The mortality risk among patients with end-stage renal disease (ESRD) and lupus is similar regardless of their initial dialysis modality, according to a new study.

Gabriel Contreras, MD, of the University of Miami Miller School of Medicine, and colleagues used propensity score matching to create 1,352 matched pairs of patients with ESRD patients and systemic lupus erythematosus (SLE) who started hemodialysis (HD) or peritoneal dialysis (PD). The matched pairs were mostly women (86%) with a median age of 39 years. The median follow-up period was 3 years.

The HD and PD groups had overall mortality rates of 22.5% and 21.4%, respectively, within the first 3 years of observation, a non-significant difference between the groups, investigators reported online ahead of print in the Clinical Journal of the American Society of Nephrology. The matched pairs also had similar cardiovascular-related mortality rates (9.5% in the HD group, 10.5% in the PD group) and infection-related mortality (4.4% in the HD group and 3.0% in the PD group).kidneyhospitalabroad@hotmail.com.

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