With the kidney function decline, creatinine, the metabolism wastes of muscle
which are supposed to be cleaned by the kidneys, would be higher than normal, so
creatnine often are as the kidney function indictor. Do you know that drugs also
can lead to high creatinine level. Why, let us have a study.
In fact, there are some medicine that are toxic to the kidney tissues, so
without a good control the taking medicine times and dosages, kidneys can be
damaged by the medicine, leading to kidney function decline, then what kinds of
drugs are bad for kidneys?
1. Antibiotics
Antibiotic is a common use drugs. It is mainly using to treat and prevent all
kinds of infection. But some antibiotics, such as Aminoglycosides,
Cephalosporin, Polymyxin and Amphotericin B, can lead to kidney function damage
and creatinine level increase.
2. Angiotensin Converting Enzyme Inhibitors (ACE)
ACE inhibitor is a kind of drugs for patients to lower down the blood
pressure. And it is the first choice for patients with kidney problem to control
high blood pressure. But some patients with impaired kidney function, such as
narrowing of the arterial vessels in the kidneys, should not take ACE Inhibitors
because they can further damage the kidneys and raise creatinine levels.
3. Diuretics
Diuretic is a common clinical drugs to relieve the edema. But long-term use
of diuretics can cause the kidney's to work overtime trying to compensate and
the result is an increase in sodium reabsorption which can further lead to
increase creatinine levels.
4. Chemotherapy Drugs
Several chemotherapy drugs like Cisplatin, Carbplatin, Carmustine, Mitomycin
and Methotrexate may cause kidney damage and produce creatinine levels increase.
Patients receiving these drugs must have labs drawn prior to administration to
check their creatinine levels to make sure that their kidneys can handle the
drugs.
5. NSAIDS (non-steroidal anti-inflammatory Drugs)
Non-steroid anti-inflammatory drugs, such as acetylsalicylic acid, ibuprofen,
butazodine, diclofenac and indometacin and piroxicam usp and so on, have the
side-effects, such as kidney failure. So it is also considered as the drugs that
can lead to creatinine level increase.
Now, you must have a clear idea about the improper drugs for kidneys, so
people should pay more attention to the medicine use under the suggestions of
doctors. Now if you want to know more information about the high creatinine
level cause and treatment, you can contact our online doctors, leave us messages
or send email to kidneyhospitalabroad@hotmail.com, we will reply you within 24
hours.
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