IgA nephropathy with hematuria as the main clinical manifestations and
identification of indicators to identify indicators of proteinuria is secondary
IgA nephropathy.
Depending on the pathogenesis of the renal edema divided clinically into two
categories:
1, nephritis edema: mainly seen in acute nephritis, or part of rapidly
progressive glomerulonephritis, chronic glomerulonephritis and other glomerular
diseases. Edema is mainly due to:
① glomerular filtration rate, renal exclusion of water, sodium reduction and
edema;
② ball - tube Imbalance: acute inflammation of glomeruli, glomerular
filtration rate was significantly lower, but the tubular reabsorption is
relatively good, the ball - loss of balance between the tubes, sodium and water
reabsorption in the renal tubules relative increase caused edema;
③ capillary hydrostatic pressure increased, the capillaries toward excessive
interstitial fluid caused the edema;
When ④ acute nephritis, some patients due to increased blood volume, blood
pressure and other causes of congestive heart failure, increased water and
sodium retention.
2, nephrotic edema: usually occurs in primary glomerular nephropathy and
other various causes of nephrotic syndrome. The main mechanism of edema are:
① plasma colloid osmotic pressure: nephrotic proteinuria caused a lot of
hypoproteinemia, caused by the plasma colloid osmotic pressure reduced, so that
the body fluid capillary filtration increases, a significant reduction in
inter-organizational recovered from body fluids, and ultimately the formation of
edema.
② effective hypovolemia: plasma extravasation make effective hypovolemia,
stimulate intravascular volume receptors, activation of the renin - angiotensin
- aldosterone system, antidiuretic hormone secretion, natriuretic hormone
secretion, tubular reabsorption of sodium increase, further exacerbating water
and sodium retention, causing edema.
IgA nephropathy with hematuria as the main clinical manifestations and
identification of indicators to identify indicators of proteinuria is secondary
IgA nephropathy. However, once the body proteinuria, so the water in the body
can not be well absorbed into the blood vessel, the water appears to occur
between the tissue penetration of the situation, this time, the patient will
appear lower extremity edema, or swelling of the face, mainly based facial
swelling and lower limb edema. For the already diagnosed as IgA nephropathy
patients, edema is a manifestation of the emergence of glomerular and tubular
function decline.
If you have problems, you can contact us by email:
kidneyhospitalabroad@hotmail.com.
No comments:
Post a Comment