What Reason of Recurrent IgA Nephropathy

First we look at the principles of IgA nephropathy proteinuria, occult blood appears, and then to analyze the reasons for the pathology can not be achieved in IgA nephropathy rehabilitation on Western medicine, Chinese medicine treatment.

Immune complex glomerulonephritis, the immune response is mainly by circulating immune complexes and in situ immune complex two ways, so multimeric IgA deposition in the mesangial area, causing intrinsic glomerular cell injury. Its antigen is mainly food, bacteria and viruses, complement activation via the alternative pathway mainly repeated the reasons IgA nephropathy primarily mucosal immune immune response in patients with abnormal occurrence and remove ineffective antigen and hepatobiliary dysfunction Clear IgA barrier, resulting in retained a large number of IgA deposition in the body and easy to mesangial area, pathological changes of glomerular intrinsic cells, permeability, macromolecules red blood cells, the protein can not be blocked, leaking from the deformation of the glomerular filtration aperture into the primary urine, which will appear to the naked eye clinic patients with IgA nephropathy occurs or inspection, proteinuria.

On the current Western medicine research level, if the simple application of Western medicine, some patients can achieve delay progression of the disease temporarily reached urine protein, occult blood was negative, but gradually recovered is quite difficult to want to treat IgA nephropathy, IgA nephropathy achieve. This is the reason repeatedly IgA nephropathy. Because the role of medicine is the largest short-inflammatory, anticoagulant, act as a "temporary" utility, temporary point of view not abnormal protein, occult items from index, which is one of medicine's characteristics: symptomatic treatment of disease. However, no such medicine which also damaged kidney inherent cells can reverse and repair utility component, this way, renal fibrosis development process can not be blocked, still slowly, illness or with the passage of time and increase. Encountered risk factors, such as colds, infections, diet, mood and other factors, proteinuria, occult blood will be a full comeback. This is like a pot of boiling water, we poured a bowl of cold water, boiling phenomenon will disappear over time, the surface was quiet, however, did not put out the fire because the Hudi, natural water boils again. That bowl of water utility only played a utility over a period of time, is not a permanent solution to inhibit water boiling.


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