IgA nephritis in children usually presents with recurrent gross hematuria,
IgA nephritis often at the same time non-specific respiratory tract infections
or gastrointestinal infections occur 1 to 2 days or gross hematuria. IgA
nephritis few children were seen in motion, fever, tonsillectomy, tooth
extraction or after trauma. Usually the rapid disappearance of gross hematuria
in a few days, no edema gross hematuria attack, no high blood pressure or other
discomfort; IgA nephritis older individual complaints of low back pain. IgA
nephritis hematuria in children with recurrent multiple times, varying the
length of the interim period, the period between the onset of urine or normal or
persistent microscopic hematuria. Renal function tests normal, some children
with IgA nephritis IgA in the blood will increase.
In the differential diagnosis in children with IgA nephropathy, there is the
need of special attention, namely: children IgA nephropathy in the disease
should be made with the four diseases in the differential diagnosis, the
specific differential diagnosis as follows:
1. Children with IgA nephropathy and nephritis in the differential
diagnosis:
Although nephritis with hematuria, however, can be identified based on a
history of allergic purpura. If necessary, the differential diagnosis by
biopsy.
2. Pediatric IgA nephropathy and lupus nephritis diagnosis:
Lupus nephritis showed microscopic or gross hematuria, often accompanied by
the performance of multi-system involvement. By checking blood complement C3,
antinuclear antibody, LE cells and biopsy, usually difficult to identify.
3. Children with IgA nephropathy and hepatitis B virus associated
glomerulonephritis in the differential diagnosis:
Hepatitis B virus associated glomerulonephritis may manifest as hematuria,
usually accompanied by a large number of urine protein, but many have
enlargement of the liver disease and abnormal liver function, HBsAg-positive and
/ or HBeAg positive.
4. Children with IgA nephropathy and acute glomerulonephritis differential
diagnosis:
More acute glomerulonephritis with hematuria as the main symptoms may be
associated with edema and hypertension, erythrocyte sedimentation rate often
faster, total complement and C3 often significantly decreased.
To sum up the four diseases must make the differential diagnosis of children
with IgA nephropathy, so as not to confuse the illness, misdiagnosis, wrong
treatment, thereby endangering the health and even the lives of children.
Shijiazhuang Kidney Disease Hospital which is a professional hospital in
treating kidney disease, you can contact us by email:
kidneyhospitalabroad@hotmail.com. to consult kidney disease.
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