Renal failure the kidney function is the portion of the total loss or
pathological condition. Renal failure is divided into renal failure and chronic
renal failure. Due to changes in kidney function will cause pharmacokinetic and
pharmacodynamic changes, therefore, when the decline in renal function should be
using drugs to master the following principles:
① understand commonly used drugs pharmacokinetic and pharmacodynamic
characteristics, when necessary, carefully read the package insert or the
Clinical Pharmacology monograph; your problem kidney disease experts have to
communicate with you by phone. If there are problems can be directly dial the
phone or online one free expert advice. We will continue to serve you to
answer!
② careful understanding of renal function and other pathophysiological
conditions (such as liver function, serum protein levels, acid-base balance and
electrolyte metabolism etc.) patient; your problem kidney disease experts have
to communicate with you by phone. If there are problems can be directly dial the
phone or online one free expert advice. We will continue to serve you to
answer!
③ familiar with renal insufficiency and other pathophysiological condition
treatment methods, the first choice in renal toxicity of drugs is relatively
small; your problem kidney disease experts have to communicate with you by
phone. If there are problems can be directly dial the phone or online one free
expert advice. We will continue to serve you to answer!
④ if it proves necessary to apply some nephrotoxic drugs should reduce the
dose according to the appropriate method, or extend the dosing interval;
⑤ certain therapeutic window (refer effective concentration range below toxic
concentration) is relatively narrow drug, if the conditions can be measured in
serum or plasma concentration of the drug (such as digoxin, theophylline,
phenytoin sodium amide aminoglycoside antibiotics);
⑥ degree of renal dysfunction should adjust the dose of certain drugs in
particular is the prototype by renal excretion of the drug, personalized
medicine. Note that drug interactions;
⑦ careful clinical observation, to discover some of the adverse reactions,
appropriate treatment promptly.
The experts in Shijiazhuang Kidney Disease Hospital which is a professional
hospital in treating kidney disease with Chinese herbal medicines can reply your
questions, welcome to consult by email: kidneyhospitalabroad@hotmail.com.
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