What Is IgA Nephropathy And Its Symptoms

Iga nephropathy is the most common worldwide diseases chronic glomerulonephritis. It should be said, iga nephropathy is a special type of glomerulonephritis, which is the mesangial area of ​​the kidney or in iga iga deposition based primary glomerular disease. Accurately speaking, iga nephropathy is not a pure type of kidney disease, but a diagnosis immunopathology name, is a group of systemic diseases, clinical hematuria glomerular nephritis disease category. Iga nephropathy is primary glomerular hematuria the most common cause, accounting for 60% -70%. According to statistics, the incidence of iga nephropathy accounts for about 26% ~ 37% of primary glomerulonephritis.

Generally believed that children iga nephropathy patients with recurrent gross hematuria patients, the majority of mild degree of renal dysfunction, the prognosis is good; and the incidence of older, accompanied by azotemia, hypertension or proteinuria, pathological changes Diffuse hyperplasia and focal glomerulosclerosis, renal tubular atrophy or interstitial fibrosis, the number of crescents more iga kidney patients, the prognosis is relatively worse. With increasing year by year the number of patients iga nephropathy, and chronic renal failure caused by the iga nephropathy is constantly increasing, statistics show that accounts for about 15% to 30%. As the existing medicine for iga nephropathy is no completely effective method, although in recent years the use of Chinese medicine treatment of iga nephropathy achieved certain results, but because of the popularity is not enough, the majority of iga nephropathy patients after standard treatment has not been able to measure the effective treatment of the disease , resulting in deteriorating condition kidney disease, renal function continued to suffer damage, so iga nephropathy patients in the direction of progress to renal failure.

IgA nephropathy clinical characteristics
1, a typical IgA nephropathy in children, often in the upper respiratory tract infection after a few hours to 2 days gross hematuria, usually lasting a few hours to several days, individual children up to one week. Such children account for about 40% to 50% of the total, IgA nephropathy in children with hematuria slightly higher performers. Clinical manifestations of individual children may have abdominal pain and severe back pain, which may be related to intestinal IgA vasculitis. Another common manifestations of IgA nephropathy in children with asymptomatic hematuria and proteinuria, 30 percent to 40 per cent of the total. 20% to 25% of patients can occur once or several times in the course of gross hematuria.

2, nephrotic syndrome, seen in 5% to 20% of IgA nephropathy patients with cases of children and young people with IgA nephropathy IgA nephropathy is more often the case with diffuse proliferative or without glomerulosclerosis. Also, sometimes mesangial IgA deposition based phenomenon can also occur in the foot process fusion with minimal change is characterized by IgA nephropathy.


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