Saturday, November 7, 2015

Three Methods to Diagnose IgA Nephropathy

Due to a variety of pathological changes IGA nephropathy, glomerulonephritis can involve almost all the pathological type, severity may be uneven. Experts teach you this in several ways, so you can quickly understand.

First, the streptococcal infection glomerular renal failure cases to determine:
Should exhibit acute nephrotic syndrome IGA nephropathy differentiated, the former long incubation period, self-healing tendencies; and IGA incubation period is short, repeated illness, combined with laboratory tests can help distinguish.
Second, according to the thin basement membrane nephropathy situation to determine:

Often persistent microscopic hematuria, often a positive family history of hematuria and renal immunopathology display IGA negative electron microscope diffuse thinning of the glomerular basement membrane. Generally not difficult to identify with the IGA open.

Third, according to IGA secondary glomerular deposition mainly to diagnose:
1, allergic purpura nephritis, purpura nephritis kidney disease management and immunopathology with IGA nephropathy same, but the former are often typical of renal manifestations, such as skin erythema, joint pain, abdominal pain and melena, etc. So these Symptoms can assist with IGA phase identification.

2, chronic alcoholic cirrhosis, 50% ∽90% of kidney tissue in patients with alcoholic cirrhosis can be displayed in the main immunoglobulin deposition IGA, but only a very small number of patients with clinical manifestations of renal involvement. Identification of the main basis of IGA nephropathy is the presence of cirrhosis.

IGA nephropathy exact pathogenesis has not been studied thoroughly, Western medicine is currently no way to cure an often require intervention from multiple levels, such as when a patient found the incidence associated with its repeated tonsil inflammation, you can consider the removal of the inflammation was controlled after the regular infection of the tonsils, and the use of hormones and other immunosuppressive drugs, but more side effects.


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