Friday, May 8, 2015

Contrast Nephropathy Associated with Long-Term Mortality in CKD

A healthcare provider may use several tests to diagnose chronic kidney disease (CKD) and determine if there is a treatable underlying cause. If one has any of the following conditions, they are at higher-than-normal risk of developing chronic kidney disease. One's kidney function may need to be monitored regularly.

Contrast-induced nephropathy (CIN) is associated with long-term mortality in patients with, but not those without, chronic kidney disease (CKD), according to a study published in The American Journal of Cardiology (2014;114:362-368).

Mitsuru Abe, MD, from the National Hospital Organization Kyoto Medical Center in Japan, and colleagues examined the effect of CIN on long-term mortality after percutaneous coronary intervention in patients with or without CKD. Data were included for 4,371 patients who had paired serum creatinine measurements before and after percutaneous coronary intervention.

The researchers found that the incidence of CIN was 5% in the study cohort overall, and 11% in patients with CKD and 2% in those without CKD. A total of 8.6% of patients died during a median follow-up of 42.3 months after discharge. After adjusting for confounders, CIN was associated with a significant 2.3 times increased risk of long-term mortality in the entire cohort. In addition, CIN was associated with a significant 2.6 times increased risk of long-term mortality in patients with CKD but a non-significant 23% increased risk patients without CKD.

kidneyhospitalabroad@hotmail.com

No comments:

Post a Comment

Any questions? Fill the form below. You'll surely get our reply very soon.