Does It Good for High or Low Creatinine

If the patient has high blood creatinine, that is mean the kidney function of the patient has problem, the ability of kidney metabolic waste is decreased, some harmful toxins can't discharge to out of body. What is the reason of patient has low creatinine?

The reasons of low serum creatinine is that after the kidney get violated by various pathogenesis, the damaged renal inherent cells of kidney appears phenotype transformation, form pathological changes, stimulate the kidney fibroblast turns into myofibroblast, at the same time, violate and stimulate the inherent kidney tissue, and occur the same lesion, then form the spread process which arrive by the dot face, from part to the overall body, go into the implement qualitative damage period(that is renal damage period ).At this time, because the kidney get damaged continuously, the function of secreting is decreased, then toxic substance such as creatinine etc accumulate in the body, increase the symptoms of increasing Serum Creatinine and Urea Nitrogen, decrease urine creatinine, decrease double kidney filtration rate etc. At the same time, the patient has other symptoms such as high blood pressure, high dropsy etc.
No matter the patient with low creatinine or high creatinine, they should pay serious attention. Creatinine substance in the body which produces by muscle metabolism creatine, through kidney the creatinine secreted to the external body. Normally, because the muscle quantity is relatively stable, so the generated quantity is constant, the level of Serum Creatinine depends on how much creatinine which is discharged by the kidney. The compensation function of kidney is strong, if a pair of kidney both normal, as long as one kidney work well, the Serum Creatinine can maintain the normal level. That is to say, only the damaged level of kidney account for more than half of the kidney, it will cause the Serum Creatinine increaseing. Therefore, the early, low-grade renal function decline can't reflected by Serum Creatinine.

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