What treatment should be taken to reduce protein in the urine effectively?

What treatment should I take to reduce protein in the urine effectively? My wife suffers from IgA nephropathy for more than 2 years. Previous test Microalbuminuria gave a result of 720 mg / l, whereas a test of urea, creatinine and uric acid showed normal values. Could you suggest what treatment should be taken to effectively reduce protein proteins? This is a request from the patient's husband. Below are some of the distractions from the response of our doctors.

Now we have a general idea of ​​the state of kidneys in your wife. While her creatinine has not yet increased, her condition is not very good.

IgA nephropathy is a disease with an immunodeficiency in which additional immunoglobulin A is deposited on mesangial cells. At an early stage, it can only affect mesangial cells, so patients often have blood in their urine. However, if kidney failure can not be controlled on time, it will damage the other part of the kidney. When the protein seeps into the urine, this indicates that the glomerular basal membrane also becomes unfavorable.

If the protein in the urine can not be controlled, it can lead to serious further damage to her kidneys. Because when proteins leak into the urine, they must pass through the glomeruli. Additional protein can be glued on the kidney capsule and glomerulus. The additional protein can cause toxicity, which leads to further damage to the glomeruli.

Therefore, the most important treatment is to restore the damaged glomeruli and stop further damage to the glomeruli. The purification therapy of toxins and osmotherapy of micro-Chinese medicine are all based on traditional Chinese medicine, they are an appropriate means for reducing protein proteins.

Have you received the answer, if you want to know more information about the treatment of protein protein reduction, you can send us an email to lovekidney2010@hotmail.com, or leave us a message, or Whatsapp / Viber +8615833993533 .

WHY IS IT CALLED IgA NEPHROPATHY AND HOW IS IT CAUSED

IgA nephropathy is very common disease, perhaps affecting several hundred million people around the globe. Although in many patients it is a rather benign disorder, it can progress to end-stage renal disease (ESRD). The clinical features of IgA nephropathy are quite variable but episodes of hematuria, often combined with persistent proteinuria, are common. Nephrotic syndrome at presentation is uncommon.

Because of the uncertain outlook, it is recommended that all people found to have IgA Nephropathy, even in its mild form, should be seen by their general practitioner and kidney specialist at regular intervals. Indeed healthy individuals with the disease should have blood pressure checks and urine examinations made by their doctor from time to time to pick up the first signs of any problems.

In those who have IgA Nephropathy regular tests of kidney function are necessary because progressive kidney failure can be detected by these tests. Even if someone with IgA Nephropathy appears to be stable, a regular review by a kidney specialist is important.

Primary IgA nephropathy (IgAN) was first described by Jean Berger. One of the difficulties in this disease3–6 is to predict at the time of the initial diagnosis the very long-term (decade) prognosis in the individual patient. This has been approached since the 1990s by the multivariate Cox regression model, taking into account the time duration of follow-up (FU) or the time elapsed since disease onset to occurrence of the events chosen as secondary or primary end points, usually chronic kidney disease (CKD, stage 3+) and end-stage renal failure (ESRF) as strong markers of progression. The predictive risk factors (RF) identified can be classified in two groups: major and the others.

So far there is no curative treatment for IgA Nephropathy. At present the most promising treatments include blood pressure lowering agents (Angiotensin Converting Enzyme (ACE) Inhibitors, Angiotensin Receptor Antagonists (ARA's) and Calcium Channel Blockers). Appropriate treatment including antibiotics for infections and diet will help in many cases, as will restriction of alcohol and tobacco intake and control of cholesterol. There is some evidence supporting the use of fish oil supplements. Rarely, other drugs, such as steroids, cyclophosphamide and mycophenolate are used for nephrotic of more rapidly progressive IgA nephropathy.

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Predicting the Risk for Dialysis or Death in IgA Nephropathy

While IgA Nephropathy occurs in all age groups, it is usually diagnosed before the age of 30 years. It is common in children but the peak incidence is between 15-25 years. Usually, the passage of blood in the urine (macroscopic haematuria) making it coffee or tea coloured, is one of the signs for which the person sees a doctor. This is usually associated with a sore throat or respiratory infection or diarrhoea and vomiting, and may occur again in association with such infections.

For the individual patient with primary IgA nephropathy (IgAN), it remains a challenge to predict long-term outcomes for patients receiving standard treatment. We studied a prospective cohort of 332 patients with biopsy-proven IgAN patients followed over an average of 13 years.

IgA Nephropathy is sometimes called Berger's disease as a French doctor, Jean Berger, was the first to describe it. Nephropathy simply means kidney disease. The antibody IgA (Immunoglobulin A), derived from the lining of the throat, air passages and intestine is found in the kidney and has caused damage to the kidney. The precise mechanism is not yet certain and is the subject of much medical research. It is thought that some people produce too much IgA antibody when their body is fighting infections of the throat, tonsils, lungs and intestines and yet the antibody produced is not as efficient in eradicating the infection as it is in most people. As a result, the antibody combines with the infecting organism (antigen), circulates in the blood and lodges in the glomerulus (the filtering mechanism of the kidney) where it causes inflammation (nephritis) which may progress to more severe kidney damage, recognised as IgA Nephropathy.

In this paper, our goal was to use these three major risk factors to calculate a simple absolute renal risk (ARR) score allowing the accurate prediction of dialysis/death event at 10 and 20 years after disease onset, in adequately treated IgAN patients and in analogy to the well-known absolute cardiovascular (CV) risk of death/CV events at 10 years.

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What Factors would Influence the Prognosis of IgA Nephropathy

IgA Nephropathy is the common CKD which refers to that patients would suffer a long term of progression of kidney disease. of cause, different patients have different prognosis with the different physical conditions, life styles, treatment options and so on. Now this article would have a introduction about the factors which influence the prognosis of IgA nephropathy, which really need the attention of patients.

Many kidney patients would become very scared once they spot gross hematuria, and they would enter uremia eventually. In fact, the severity and frequency of hematuria has no direct relationship with the prognosis of the IgA Nephropathy. In general, the progression of IgA Nephropathy is slow, and this disease is less likely to progress into kidney failure than other types of kidney disease.

With that being said, patients with IgA Nephropathy should take this disease seriously. So patients should visit their doctors on a regular basis, stick with the treatment and do not cut back on medications on their own.

The major factors that influence prognosis of IgA Nephropathy include:

1. the gender of the patient: female patients tend to have better prognosis than male patients.

2. the starting age: on average, the children’s prognosis is better than adults. The prognosis for patients whose starting age is above 40 years old is usually not good.

3. patients whose GFR is already low and who has already kidney damage tend to have gloomy prognosis.

4. patients with less proteinuria tend to have better prognosis.

5. patients with normal blood pressure have better prognosis than patients with high blood pressure.

6. patients with the following pathological changes tend to worse prognosis: diffuse, proliferative glomerular damage with the formation of segmental or diffuse crescent, focal and segmental glomerular hardening or tubular atrophy, hardening arteriola, the thickening of the walls, the interstitial fibrosis and the deposits of IgA and C3.


Now if you want to know more information about the factors which influence the prognosis of IgA Nephropathy or ask for treatment suggestions, you can contact our online doctors, leave us messages or send email to kidneyhospitalabroad@hotmail.com, we will reply you within 24 hours.

High Fever in Patients with IgA Nephropathy: Cause and Treatment

Some IgA Nephropathy patients may suffer from high fever, with the chronic and persistent high fever, other tissues are bothered and influenced. The sever pains also urge patients to know the cause and management for the high fever in IgA Nephropathy.

Let′s talk about fever firstly. In fact, fever is the body′s natural way to protect itself from invaders like bacteria and virus, because many of them are no able to survive in the body due to the high temperature caused by a fever.
High temperature is also a signal that the infection-fighting cells of the immune system including phagocytes, neutrophils, and lymphocytes come to the body′s defence and assist with fighting against infections.

Causes of high fever in IgA Nephropathy

IgA Nephropathy is a chronic form of glomerulonephritis marked by a hematuria and proteinuria and by the depositions of immunoglobulin A in the mesangial areas of the renal glomeruli, with subsequent reactive hyperplasia of mesangial cells. Upper respiratory tract infection often happens before the onset.

High fever in IgA Nephropathy may appear as a result of infection. When people are affected by an infection, or inflammation, the body will produce substances called pyrogens. It is the pyrogens that actually cause the high fever.

Symptoms of high fever in IgA Nephropathy

If persons with IgA Nephropathy have a high fever, the muscles might repeatedly contract to keep the body warm, causing shivering. Sometimes, chills occur when this happens.

IgA Nephropathy is not a benign disease, and many people may progress into Renal Failure if improperly treated. At present, Micro-Chinese Medicine Osmotherapy is the latest treatment for IgA Nephropathy, which can guarantee the best curative effects.


Now if you want to know more information about the cause and management for high fever in IgA Nephropathy, you can contact our online doctors, leave us messages or send email to kidneyhospitalabroad@hotmail.com, we will reply you within 24 hours.

Urine Change in IgA Nephropathy: Cause and Management

Urine change is the common sign of kidney function disorder. So when people are attacked by IgA Nephropathy, patients may find disorder in their urine. How the proper symptoms in urine may occur, patients can have a timely prevention and treatment. This article would have a analysis.

Hematuria can be found by observing urine. Hematuria can be divided into gross hematuria and microscopic hematuria. Simply speaking, gross hematuria or macroscopic hematuria refers to that the urine is bloody, which is visible to the naked eye. So if you find you have blood urine for 3 to 7 days and you have no history of hurting urinary tract, you had better to see a doctor and take a urine test.

To patients with IgA Nephropathy, their urine will be dark in 3 days after some infections, such as cold. The dark red urine can last for several days to even several weeks, then the color of urine turn to light. It is necessary for people to take a urine test after one week dark urine. Usually, gross hematuria means that their kidneys are under the situation of acute glomerulonephritis, and microscopic hematuria means that their kidneys are under microinflammation state. Due to inflammation, calculus, tumor, injury, congenital malformation are the common causes for hematuria, if you want to make sure the real reason, you can take blood test or test for kidneys.

Bubbles in urine is another signal for IgA Nephropathy. If you have bubbles for more than one month and you have no Diabetes, the bubbles in urine maybe leaked protein. You should pay attention first to make sure you don′t have too much protein, then observe the urine again. If the bubbles still in urine, it maybe proteinurine.

we know, glomerulus blood capillary has good permeability on water and electrolyte, but big molecular protein can not be eliminated from the glomerulus blood capillary. So, protein urine can indicate the damage on glomerulus blood capillary. Most patients with IgA Nephropathy has proteinurine and over 60% of them go to see a doctor for bubbles in urine.


IgA Nephropathy patients should have a timely and effective treatment when there are some disorder in their urine, you can contact our online doctors, leave us messages or send email to kidneyhospitalabroad@hotmail.com for more questions or ask for treatment suggestions, we will reply you within 24 hours.

Corticosteroids Okay for IgA Nephropathy Regardless of Renal Function

In many parts of the world, IgA nephropathy is the most common form of glomerulonephritis--a disease that damages the tiny filtering units of the kidney, called glomeruli. IgA nephropathy (nuh-FROP-uh-thee), also known as Berger's disease, is a kidney disease that occurs when an antibody called immunoglobulin A (IgA) lodges in your kidneys. IgA nephropathy usually progresses slowly over many years, but the course of the disease in each person is uncertain. Primary IgA nephropathy is characterized by deposition of the IgA antibody in the glomerulus. In IgA nephropathy there is a slow progression to chronic kidney failure in 25-30% of cases during a period of 20 years.

Using corticosteroids (CS) to treat patients with IgA nephropathy decreases the risk of disease progression regardless of initial estimated glomerular filtration rate (eGFR), new research suggests.

Current guidelines suggest CS treatment in patients with IgA nephropathy (IgAN) when eGFR is higher than 50 mL/min/1.73 m2 and proteinuria is persistently 1 g/day or more despite 3–6 months of supportive care. Whether the benefits of this treatment extend to patients with an eGFR of 50 mL/min/1.73 m2 or below, other levels of proteinuria, or different renal pathologic lesions remains unknown, according to researchers.

In a retrospective study, Rosanna Coppo, MD, of Turin Hospital in Turin, Italy, and colleagues analyzed data from 1,147 patients with IgAN from the European Validation Study of the Oxford Classification of IgAN (VALIGA) cohort. Physicians prescribed immunosuppression for 46% of the patients. Of these, 98% received CS.

Using a propensity score, the investigators matched 184 patients who received CS and renin-angiotensin system blockade (RASB) to 184 patients with a similar risk profile of progression who received only RASB. At the time of biopsy, 115 of the 368 patients had an eGFR of 50 mL/min/1.73 m2 or less (54 who received RASB alone and 61 who received CS and RASB) and 253 had an eGFR above 50 mL/min/1.73 m2 (130 who received RASB alone and 123 who received CS and RASB).

In the propensity score-matched subgroup, CS treatment decreased proteinuria and the rate of renal function decline and increased renal survival, Dr. Coppo's group reported online ahead of print in the Journal of the American Society of Nephrology. During the entire follow-up, mean proteinuria values declined by 0.8 g/day in the CS-RASB group compared with a decline of 3.2 g/day in the RASB group. Renal function declined by 1.0 mL/min/1.73 m2 per year in the CS-RASB group versus a decline of 3.2 mL/min/1.73 m2 per year in the RASB group.

A total of 84 patients in the CS group experienced a reduction in proteinuria to less than 1 g/day compared with 54 patients in the RASB group. A reduction in proteinuria to ESRD developed in 7 patients in the CS-RASB group compared with 20 in the RASB group. All of these between-group differences were statistically significant.

These benefits extended to patients with an eGFR of 50 mL/min/1.73 m2 or less, with the benefits increasing proportionately with the level of proteinuria. Among the patients in this subgroup, eGFR declined by 0.3 mL/min/1.73 m2 per year in the CS-RASB recipients compared with a decline of 4.8 mL/min/1.73 m2 per year in the RASB group. In addition, 74% in the CS group reached a proteinuria level below 1 g/day compared with 37% of the RASB group.

“Although this retrospective analysis cannot provide an explicit recommendation for the use of CS within this group until randomized trials confirm our findings, clinicians should consider this option, especially in those with an elevated proteinuria despite optimal conservative therapy,” the authors concluded.

To sum up, you can know about  corticosteroids okay for igA nephropathy regardless of renal function. If you want to know more information, you can send email to kidneyhospitalabroad@hotmail.com.  You can contact us online doctors.

Symptoms and Signs of High BUN in IgA Nephropathy

With the increasing of kidney disease patients in recent years, it is necessary for us to understand the knowledge about kidney disease .Do you know what are the symptoms of high Blood Urea Nitrogen(BUN)in LgA Nephropathy. I think it is better for us to prevent the happening of the kidney disease effectively, if we know enough Kinney disease knowledge. Now I will communicate the symptoms and signs of high BUN in LgA Nephropathy, which I hope will benefit to you.

Symptoms and signs of high BUN

1 Nausea and vomiting

When the patient’s kidney function is declining ,the BUN can be permeated into gastrointestinal tract with the blood circulation, and when the urea are degraded into ammonia at the work of bacterial enzymes, the ammonia would cause damage to gastrointestinal

2 Bad taste in mouth.

Along with the blood circulation, digestive tract and breath system, the ammonia can enter into mouth; this is why there are bad tastes in odor.

3 Skin itching

We know that everybody will sweat everyday, when the urea is excreted out of body with the sweat; patients with LgA Nephropathy would suffer the dry skin, and even leading to skin itching.

Beside above, there are still some other symptoms, such as high blood pressure, fluid retention, insomnia and bone fracture.

Treatments

I believe that the patients with high BUN in LgA Nephropathy must want to get rid of the symptom. There is an effective therapy to treat this disease; it is Micro-Chinese Medicine Osmotherapy.

The active substances in medicine has functions of expending blood vessels, promoting blood circulation and removing blood clots, and with the accumulated blood circulation and increased blood perfusion, the deposition of IgA can be decreased and the GFR also can be improved.


If you want to know more information about Micro-Chinese Medicine Osmotherapy or other special therapies in our hospital, you can contact with our online doctors or send Emails to kidneyhospitalabroad@hotmail.com, we are willing to answer all your questions.

Joint Pain in IgA Nephropathy: Cause and Treatment

Nowadays, the LgA Nephropathy has aroused many kidney patients’ attention, as we all know, LgA Nephropathy is caused by immune system disorder and there are a lot of tiresome complications, such as joint pain. It is necessary for patients of LgA Nephropathy to know the reasons and treatment about LgA Nephropathy with joint pain.

Causes

1 lacking of calcium

The kidney is an important metabolish organ of our body, which can transform vitamin D to Clairol that our body needed. When the patients cause LgA Nephropathy, the kidney function is declining, so it has not enough ability to transform Clairol. The main function of Clairol is promoting calcium absorption, there is less calcium, and as a result the patients will fell joint pain.

2 And excess of uric acid

Because of falling of the kidney function, a lot of uric acid is detained in the blood. As time going on, the uric acid will become crystallization gradually, when these crystallization exist in bone, the patients will fell pain.

3 Side function of medical

The patients with LgA Nephropathy must be use kinds of medicines. There is no denying that any western medicine has side effecting, for example, the steroids and immunosuppressants in the medicine will lead to joint pain.

Treatment

We know that the joint pain has impacted patients’ normal life seriously, if you want to get rid of joint pain , the most fundamental way to treat the kidney. So I will introduce two effective therapies which I hope will help you.

1 Acupuncture therapy

Acupuncture is a traditional Chinese medicine treatment of the progenitor treatment, which has been introduced to Chinese medicine in the early spring and Autumn period. As we all know there are a lot of acupuncture points in our body, and different point has different function to our body. So our hospital according to the points to treat kidney disease, which has gain a great achievement. Through pricking patients’ points, get through the main and collateral channels of patient. So reach to the purpose of getting rid of poison, dampness, cold and all kinds of disease. Through the therapy , we improve the function of kidney and promote calcium absorption, at last ,the joint pain will be reduced.

2 Foot bath therapy

Without to say, everyone has the habit of washing foot before do to the bed on the night, after wash foot we will fell comfort and can have a good sleep. The foot bath therapy is another achievement in our hospital; we crush all kinds of Chinese herbs into powder, and mix them with hot water. The most important thing is the time, you are suppose to remember that it is better to having foot bath at night and must last tow hours. After the foot bath, the blood circulation of our body will be promoted, the cold air in our body will be taking away, and some poison also can be discharged. If you insist it for a long time, the therapy of joint pain will be getting rid of.


There are still numerous excellent Chinese therapies in our hospital to treat LgA Nephropathy, if you want to know more information about our therapies, you can communicate with our online doctors, or send email to kidneyhospitalabroad@hotmail.com we hope that you get well soon and live a better life.

Healthy Diet plan for IgA Nephropathy

The patients with IgA Nephropathy must be told by doctors should pay more attention to their daily diet. A healthy diet is very important to kidney disease patients; it can delay the development of LgA Nephropathy and remit some symptoms. Now I will make a wonderful introduce about healthy diet plan for LgA Nephropathy.

1 low protein

There will be a heavy burden to kidney if patients intake a lot of food with protein. It can produce protein urine, leading to further kidney damage. The food, such as beans and bean products are forbidden. However, we still need some high quality protein food, including eggs, lean meet, fish and milk which can provide amino acid for human body. What’s more? They can’t burden kidney.

2 low salts

High salts can lead to water-sodium retention, which worsen edema and high blood pressure.

3 low fats

The root of kidney disease is arteriosclerosis, while if patients eat too many fats the glomerulus arteriosclerosis will become serious.

4 low potassium

There are potassium in our blood, with the function of kidney declining, patients who eat too much potassium maybe occur hyperkalemia easily. That can lead to sudden cardiac arrest which is very dangerous, such as bananas, tomatoes, orange should be avoided.

4 low phosphorus

High phosphorus can impact calcium metabolism, as a result, it can lead to some symptoms, such as muscle cramp, skin itching and bone disease.

What do you think what I say, if you think its are helpful to IgA Nephropathy you can communicate with our online doctors, and if you want to know more information about kidney disease you also can send email to kidneyhospitalabroad@hotmail.com. At last, we hope you live a better life.

Treat Flank Pain Caused from IgA Nephropathy

Many patients with IgA Nephropathy have symptoms, such as protein urine, blood urine and high blood pressure. Of course, there are some patients who are caring about the treatments for flank pain. Flank pain often starts as a little discomfort in the area above one or both kidneys.

There are no good medical treatments for flank pain. Aspirin can aggravate bouts of gross hematuria, and doctors warn against using it in children and teenagers whenever there is a possibility of a viral infection because of the danger of developing Reye’s Syndrome. Acetaminophen (Tylenol) and ibuprofen (Motrin, Advil) are both nephrotoxic and should not be taken in quantity for any type of pain, including headaches. Besides, painkillers appear to have little effect on flank pain. Similarly, sedatives and muscle-relaxants like Valium do little once an attack is underway, nor is there evidence that such heavy-duty painkillers as Demerol or nerve blocks are effective.

It’s also a good idea to stay away from caffeine, alcohol, and tobacco during any exacerbations of the disease. The Network has also received reports that repeated bending and overuse of the back may aggravate flank pain. If this is a feature of yours work, you may need to speak to your employer about possible modifications to your job. If you are interested in Chinese medicine in treating IgA Nephropathy, feel free to send us an email to doctornickzhang@hotmail.com, or you can leave us a message.

Treat Proteinuria for Patients with IgA Nephropathy

How to treat proteinuria for patients with IgA Nephropathy? Moderate quantity of proteinuria means that the 24 hours′ protein quantity is among 1 to 3 grams. It is usually considered that patients should take medicine to reduce protein in urine and protect renal function. The medicine is main with angiotensin-converting enzyme inhibitors, which can reduce the filtration of protein from glomerulus and thus protects glomerulus from further damage. Besides, it can also prevent glomerulus mesangial cell′s wall thickened.

In addition, it is considered that the patients can take moderate dosage of Hormone Medicine to inhibit the special inflammation reaction of kidney.
However, the common treatment usually treats blood urine, which is the symptom of IgA Nephropathy , and it can not repair the damaged glomerulus mesangial cell or prevent the renal function from further decline .Micro-Chinese Medicine Osmotherapy combines the treatment of Western Medicine and Traditional Chinese Medicine to treat the disease from the root by repairing the damaged glomerulus mesangial cell and protecting the renal function from further decline, which goes through four processes such as dilating vessel blood, anti-inflammation, anti-coagulation and degrading extracellular matrixes.

If you still have any follow-up questions about treatment for proteinuria in IgA Nephropathy, you are welcomed to leave us a message or send us an email to doctornickzhang@hotmail.com, then our expert will contact you as soon as possible.

Life Expectancy for IgA Nephropathy

What’s the lifespan of IgA Nephropathy patients? About this question, answers differ from different conditions of patients. But one thing is sure, their lifespan depends on their treatment, diet and attitudes.

The first factor connected with patients’ lifespan is treatment. Right treatment improves their life quality in a large degree. Then what is right treatment? Recently, many treatments can eliminate the symptoms effectively and rapidly, which blinds patients’ eyes. It seems that they are cured. In fact, as these treatment only eliminate symptoms instead of starting from the root cause, these symptoms may appear again easily. Therefore, patients should choose a scientific treatment which takes up from repairing damaged renal functions, thus eliminates recurrent symptoms from the root.

Another factor which can delay or prolong patient’s lifespan is daily diet. Patients should take the following principles in their minds.

-Keep a low intake of water in order to lighten the burden from edema. Water volume should be based on the urine quantity of last day.

-Eat more fresh vegetables and fruits to replenish necessary nutrition. If convenient, patients can take some fish oil which can decrease blood fat, blood pressure and blood colts. Besides, long-term intake of fish oil can also remedy focal proliferative Nephropathy and Proteinuria induced by membranous nephropathy.

-Take low-quantity but high-quality protein food to provide enough protein and decrease renal workload. Animal protein is better than plant protein.

-Limit the intake of salt. Excessive salt can lead to water and sodium retention, thus aggravating edema.

The last factor affecting lifespan of IgA Nephropathy is patients’ attitude to IgA Nephropathy. Surveys show that positive attitude is a key point to turn patients’ condition better. If you still have any questions about life expectancy for IgA Nephropathy, you can leave us a message or you send us an email to doctornickzhang@hotmail.com.

Diet for IgA Nephropathy Patients

Diet may play a very important role in the recovery or the treatment for IgA Nephropathy patients. So the patients or their families should know something about the diet for IgA Nephropathy. Here Chinese experts recommend you some proper foods for IgA Nephropathy patients.

1. Be a vegetarian.
2. Have high-quality-protein food like lean meat, and chicken; Egg white is also ok. Avoid beans and bean products. Limit the intake of the protein or they will burden the kidney.
3. Limit your salt intake ― to help manage your blood pressure. A low-salt diet can also help minimize fluid retention and swelling.
4. Limit the foods with high potassium, such as bananas, tomatoes, oranges etc.
5. Avoid cold or it will aggravate the damage of kidney.
6. IgA Nephropathy patients can not eat spicy food, seafood, beef, mutton, crabs, garlic, onions, parsley, dog meat and wine, coffee, seasoning and other stimulating food and don’t eat animal livers.
7. Fish and Fish Oil is recommended for IgA Nephropathy

In addition to the patients paying much attention to their diet, they had better chose the correct and effective treatment in time.
If you still have any follow-up questions about diet for IgA Nephropathy patients or you want to know its natural treatment, you are welcomed to leave us a message or you can send us an email to doctornickzhnag@hotmail.com.

IgA Nephropathy: High Creatinine Level And Prognosis

When kidney damages develop seriously, high creatinine levels will send a signal. The following information is about high creatinine level in IgA Nephropathy and its prognosis.

Creatinine is a kind of micromolecule urotoxins, which is the byproduct of muscle activity. In normal condition, these urotoxins will be filtered out by kidneys and keep your blood and body healthy. However, once your kidneys cannot cleanse them out, it will elevate the levels of creatinine.

Creatinine reflects the kidney function levels, however, it is not fast enough. Only when kidney functions decline more than 30%~50%, the creatinine levels goes up later on.

Thereby, to monitor the early kidney damages, you are suggested with the specific test for early kidney damages, such as β2 microglobulin, CysC, HCY, RBP, RBP etc. These tests are smarter than creatinine to monitor kidney condition, which are especially recommended to people with diabetes, high blood pressure and whose family member suffering from kidney disease.

Once high creatinine levels occur, it indicates that IgA Kidney Disease patients have developed into a serious kidney damages. In this condition, the treatment that only controls the symptoms by limiting the inflammation is not enough. Patients are suggested to improve kidney functions in a short time. Otherwise, you may miss the key time and wait for kidney falling and go on dialysis or register on waiting list.

Generally speaking, the prognosis of IgA Nephropathy is good. Its prognosis mainly depends on the following factors.

1.Usually, the prognosis of male patients with IgA Nephropathy is bad. Moreover, the elder the patients are, the worse its prognosis will be.
2. The prognosis of the patients with frequent gross hematuiria is bad.
3. If the patients are accompanied with a mass of protein in urine, the prognosis is bad.
4. If the blood pressure is beyond control, the prognosis of IgA Nephropathy is bad.
5. The patients with serious pathological changes, its prognosis is worse.

Deal with Hematuria in IgA Nephropathy

IgA Nephropathy (Berger′s Disease) patients appear to have microscopic hematuria and gross hematuria.The symptoms are mainly caused due to damages of glomerular filtration membrane. How to deal with hematuria?

1. The best way to prevent hematuria is to have regular and balanced diet. Never eat something too salty or too greasy. Eat less meat. Eat more vegetables. Develop a good habit of drinking water in daily life.

2. Do proper physical activities regularly.

3. Have a correct understand of hematuria and do not be too worried. Gross hematuria refers to 1~3ml blood in 1000ml urine, so it will not cause serious blood loss.

4. Keep a balance between work and rest. Avoid over-strain work and strenuous exercise.

5. Treat inflammatory disease, such as urinary tract infection, etc positively.
Apart from taking daily nursing care, IgA Nephropathy patients should be clear that only with effective treatment, can you get rid of hematuria permanently. If you are interested in the natural and efficient treatment for IgA Nephropathy, you can send us an email to doctornickzhang@hotmail.com, or you can leave us a message.

The Foods That IgA Nephropathy Patients Should Avoid

Animal livers.
IgA Nephropathy patients can not eat or less eat the food rich in cholesterol, such as animal internal organs-livers or hearts and they should eat more food rich in fatty acid(such as plant oil, deep sea fish oil)and food rich in fibrin, such as green vegetables, celeries and so on.

Meat and fish
All the Kidney Disease patients including IgA Nephropathy ones need to follow what the doctor suggested and avoid to eat meat and fish during the Festivals. They should stick to the eating habits as usual.
This is because meat and fish are diet taboos for Kidney Disease patients who should have ‘quality low-protein’ diet and they also belong to high-fat foods(mainly including cholesterol and triglycerides). A high-fat diet will not only aggravate the damage to the patients’ kidney but it also can damage the kidney of the healthy people.

Fried foods
Use vegetable oil to cook food and eat less Fried foods. Eat little peanuts, because they contain much oil. But the patients can eat some walnuts, sunflower seeds, nut let and so on.

In addition, IgA Nephropathy patients cannot eat spicy food, seafood, beef, mutton, crabs, garlic, onions, parsley, dog meat and wine, coffee, dressings and other stimulating food. IgA Nephropathy patients should not eat any tonic food and hot food, such as chili, litchi, chocolate, etc. The patients are yin deficiency with purple tongue, astringent pulse, hard breath, abdominal distension and so on should keep the diet taboo in mind.

If you still want to know more about diet for IgA Nephropathy or its natural treatment, you can send us an email to doctornickzhang@hotmail.com.

Chinese Herbal Medicine for IgA Nephropathy

If you are suffering from IgA Nephropathy, the following information about pathogenesis and treatment for IgA Nephropathy can be helpful.
In fact, the pathological changes of IgA Nephropathy are caused due to IgA and immune complex deposits in mesangial area of the glomeruli. So renal ischemia and anoxia will appear. Gradually, part of the glomeruli become impaired or scarred, and even sclerosed finally. Glomeruli function as the filtering units of the kidneys and are in charging of cleaning the blood. With scarred glomeruli, big molecules like proteins and red blood cells will spill out into the urine, resulting in proteinuria and hematuria.Metabolic disorders can also appear, so wastes products like BUN, uric acid, creatine, etc will buildup within patient′s body.

Chinese herbs have long been used to treat many diseases in traditional Chinese medicine(TCM), and their curative effects are also significant. However, the decoction tastes bitter and long-term application will also cause digestive ailments.

To overcome the above incompetent sides of traditional Chinese herbs, nephrologists in our hospital create an innovative therapy-Traditional Chinese medicine iontophoresis with our own equipment. It is an external application. The Chinese herbs are micronized into granules which can be permeated into lesions directly with the help of modern osmosis technology.

Traditional Chinese medicine iontophoresis can remove the IgA and immune complex deposited in masangial area by improving blood circulation. Then the states of ischemia and anoxia will be remitted, and further damages to the glomeruli can be prevented. Moreover, Chinese herbal medicine can provide abundant micronutrients to repair the impaired or scarred glomeruli as well as improve overall immunity.

If you are interested in Chinese herbal medicines in treating IgA Nephropathy, you are welcomed to leave us a message or you can send us an email to doctornickzhang@hotmail.com.

What Symptoms of IgA Nephropathy Are You Suffering

In the early stage, IgA Nephropathy has no obvious symptoms, so the disease is easy to be ignored by patients, and then the best time for treatment is delayed. Here the following are six common symptoms of IgA Nephropathy.

● High blood pressure
Some patients with IgA Nephropathy can also get high blood pressure which is not a good thing to patients. High blood pressure can speed up the deterioration of kidney function and push the condition to stage of Uremia. So blood pressure control is very important.

● Swelling
In clinical, some patients with IgA Nephropathy will get swelling. The decrease in volume of urine and frequent micturition may also appear. Swelling usually appears on hands, feet, ankles and eyes.

● Anemia
Because the kidney function has been damaged, the body can not produce enough erythropoietin, so anemia appears. Patients often feel cold and fatigue when they get anemia.

● Under the weather
Lots of toxins and metabolic wastes continuously deposit in body, because of the decrease in kidney function. A series of symptoms such as nausea, vomit, sleep problems, loss of appetite, titillation and fatigue will appear.

● Proteinuria
In general, the Urine Protein Quantitation(UPQ) is less than 1g/24h, however, the minority of patients will get a great quantity of proteinuria and even Nephrotic Syndrome.

● Onset gross hematuria
Gross hematuria is more common in children and usually appears after the upper respiratory tract is infected, and at times, after the acute gastroenteritis or urinary tract infection. The spacing interval is 24 to 72 hours.

What is The Safe Treatment for IgA Nephropathy Patients? The symptoms of IgA Nephropathy are usually treated by the western medicines. If IgA Nephropathy patients want to avoid dialysis and kidney transplant efficiently, a real treatment which can treat the disease from the root seems to be very important.

Henoch-Schönlein Purpura Nephritis Causes and Its Relationship with IgA

Henoch-Schönlein purpura nephritis is a rare kidney disease leading to chronic kidney disease. Although retrospective studies suggest beneficial effects of some therapies, prospective randomized clinical trials proving treatment efficacy are still lacking. In view of this, we should find out its causes and then prevent them.

Henoch-Schonlein purpura is a type of vasculitis and inflammatory response within the blood vessel that has symptoms of purple spots on the skin, joint pain, gastrointestinal symptoms, and glomerulonephritis. It is usually seen in children (more commonly boys than in girls), but people of any age may be affected. Many have had an upper respiratory illness in the previous weeks. However, the pathogenesis of HSP remains unknown.

It is generally considered to be an immune complex-mediated disease characterized by the presence of polymeric IgA1containing immune complexes predominantly in dermal, gastrointestinal, and glomerular capillaries. The pathognomonic granular IgA and C3 deposits in the mesangium are indistinguishable from those seen in IgA nephropathy. Similar immunohistologic findings have also been observed in the kidneys of patients with liver cirrhosis, dermatitis herpetiformis, celiac disease, and chronic inflammatory disease of the lung.

The relationship between IgA nephropathy and HSP remains obscure, since the pathogenesis of both are still enigmatic despite the considerable information presented. However, a good deal of evidence suggests that the two disorders are pathogenetically linked. Many (but not all) patients with both disorders have increased serum IgA levels and IgA-containing CIC. Other observations in favor of a hypothesis of commonality include the indistinguishable nature of the renal histopathologic lesion, the presence of clinically silent but histologically detectable IgA deposits in dermal and gastrointestinal tissue in patients with Berger's disease, and the occasional report of HSP occurring in patients with prior long-term IgA nephropathy. Finally, one of two identical twin brothers simultaneously infected by proven adenovirus developed severe HSP nephritis progressing to chronic renal insufficiency, while the other developed Berger's disease with recurrent asymptomatic hematuria.