High Creatinine Level in Nephrotic Syndrome

For Nephrotic Syndrome patients, they may notice the high creatinine if the condition is not controlled well. The creatinine level will not increase obviously until more than a half of kidney function has been lost. So high creatinine level means severe kidney damage and poor kidney function. Then why can high creatinine happen in Nephrotic Syndrome?

When kidney is violated by all kind of pathogenesis, the damaged kidney inherent cells will get phenotype transformation first, which can form pathological change and stimulate fibroblasts to transform into myofibroblasts, and meanwhile violate and arouse normal kidney tissues to get the same pathological changes, so it has formed a spread process from part to whole and enter the renal damage period. At this moment, because of constant damages of kidney and decrease of function of excreting the wastes, creatinine and other toxins will accumulate in the body, and then high creatinine level appears. Nephrotic Syndrome patients may also get high blood pressure, dropsy and other symptoms.

The appearance of high creatinine also can be explained using inherent cells and extracellular matrix.

All kinds of primary and secondary pathogenesis act on glomerulus continuously for a long time, which can stimulate glomerular local microcirculation barrier and cause the damage of the glomerular capillary endothelial cells. Inflammatory cells in blood circulation will get infiltration and release inflammatory mediators which can cause disease. The progress of kidney fibrosis starts, when mesangial cells are damaged and shrink, the filtration area of glomerulus will declines, meanwhile, the damaged inherent cells will secrete and synthetize a series of ECM that can not be degraded by matrix metalloproteinases (MMP), which stimulates glomerulus induration and renal interstitial fibrosis. A number of creatinine can not be leaked normally but enter blood circulation, which causes high creatinine level.

In order to treat Nephrotic Syndrome from the root, we need to make clear which type of Nephrotic Syndrome patient is suffering. Then the key of High Creatinine Treatment in China should be repairing kidney damage and enhancing kidney function, not lowering high creatinine. After the kidneys regain health and they can work normally again, the creatinine level will go back to the normal level naturally.

What Symptoms of IgA Nephropathy Are You Suffering

In the early stage, IgA Nephropathy has no obvious symptoms, so the disease is easy to be ignored by patients, and then the best time for treatment is delayed. Here the following are six common symptoms of IgA Nephropathy.

● High blood pressure
Some patients with IgA Nephropathy can also get high blood pressure which is not a good thing to patients. High blood pressure can speed up the deterioration of kidney function and push the condition to stage of Uremia. So blood pressure control is very important.

● Swelling
In clinical, some patients with IgA Nephropathy will get swelling. The decrease in volume of urine and frequent micturition may also appear. Swelling usually appears on hands, feet, ankles and eyes.

● Anemia
Because the kidney function has been damaged, the body can not produce enough erythropoietin, so anemia appears. Patients often feel cold and fatigue when they get anemia.

● Under the weather
Lots of toxins and metabolic wastes continuously deposit in body, because of the decrease in kidney function. A series of symptoms such as nausea, vomit, sleep problems, loss of appetite, titillation and fatigue will appear.

● Proteinuria
In general, the Urine Protein Quantitation(UPQ) is less than 1g/24h, however, the minority of patients will get a great quantity of proteinuria and even Nephrotic Syndrome.

● Onset gross hematuria
Gross hematuria is more common in children and usually appears after the upper respiratory tract is infected, and at times, after the acute gastroenteritis or urinary tract infection. The spacing interval is 24 to 72 hours.

What is The Safe Treatment for IgA Nephropathy Patients? The symptoms of IgA Nephropathy are usually treated by the western medicines. If IgA Nephropathy patients want to avoid dialysis and kidney transplant efficiently, a real treatment which can treat the disease from the root seems to be very important.

How to Help Nephrotic Syndrome Patients Lower High Creatinine

How to help Nephrotic Syndrome patients lower high creatinine? The high creatinine in Nephrotic Syndrome indicates severe kidney damage which exceeds the compensation function of kidney itself. In general, high creatinine will not appear in Nephrotic Syndrome until more than a half of kidney function has been lost.

High creatinine means the severe kidney damage and poor kidney function. So once high creatinine happens, Nephrotic Syndrome patients should pay more attention and take the treatment as early as possible. If the kidney function keeps declining, creatinine level will keep increasing and the condition will enter Kidney Failure which needs dialysis or kidney transplant in the near future. When dealing with the problem of high creatinine, we must start with the root cause. Do you know What is the Best Way to Get Rid of High Creatinine?

As to the treatment for high creatinine in Nephrotic Syndrome, the best way is to prevent kidney fibrosis fundamentally, in case that kidney inherent function and cells keep being destroyed. Micro-Chinese Medicine Osmotherapy is a special therapy. Immune complex depositing in kidney causes kidney diseases. So if we want to treat Nephrotic Syndrome, immune complex is the key. Micro-Chinese Medicine Osmotherapy discharges the sloughs out of body and repair the damaged inherent cells. Micro-Chinese medicine osmotherapy can provide a clean inner environment for the following treatments. Micro-Chinese Medicine can provide repairing substances, such as various vitamin, trace elements, organic acid, amino acid etc. to the injured kidney. After the Micro-Chinese Medicine enters the injured tissues, they can stimulate the DNA of the damaged cells to compose and also accelerate their replication, which, thus promotes the recovery of the renal function. Micro-Chinese Medicine Osmotherapy is used externally. Nephrotic Syndrome patients just need to lie on the bed to take this treatment.

How to Help Patients with Creatinine 4.1

How to help patients with creatinine 4.1? Creatinine level can indicate that how kidney function is to some extent. Creatinine will not increase until the kidney function has declined to at least 50%, that is because our kidneys have the strong compensatory ability. If creatinine is 4.1 which is much higher than the normal range, we can say that less than 50% of kidney function is left. Also creatinine 4.1 is in the stage 3 of CKD, which means the illness condition still has the possibility to be reversed.

High creatinine levels troubles kidney disease patients a lot. It will cause nausea, vomiting, poor appetite, metabolic acidosis, hyperkalemia or hypokaliemia, hypocalcemia and high phosphorus and so on. Dialysis will be used when creatinine level is about 5 in most countries and dialysis does lower creatinine level in a short time. But in China, parents are not advised to undergo dialysis unless high creatinine has already caused some severe symptoms. We do believe that dialysis should not accompany patients for the rest of their life, and there must be some treatment that can help them get rid of dialysis and recover their kidney function. What Creatinine Level Is for Dialysis?

We will need Micro-Chinese Medicine Osmotherapy to help patients with creatinine 4.1 avoid Kidney Failure and dialysis. Stage 3 chronic kidney disease is a very urgent stage to receive treatment. Micro-Chinese Medicine Osmotherapy is used externally, patients just need to lie on the bed to take this treatment. The active materials can expand blood vessels, promote blood circulation, remove blood stasis and provide nutrient for damaged kidneys. If the kidney damage can be repaired, kidney function will recover gradually, then dialysis and Kidney Failure will be avoided greatly. Patients with creatinine 4.1 don’t have to worry about the side effects, all the medicines come from the nature.

When should Renal Failure Patients Take Dialysis

When should Renal Failure Patients Take Dialysis

It is very common that dialysis will be used for Renal Failure patients. And high creatinine levels usually happen in patients with Renal Failure. Generally speaking, dialysis will be recommended when creatinine levels reaches to about 5 while in China, it is 8. As a matter of fact, the creatinine levels has no direct relation with dialysis, that is to say, only a creatinine level can not decide whether dialysis is needed or not. In clinical, some patients have already started dialysis even though their creatinine level doesn't reach to 5 and also there are many patients have not begun dialysis though their creatinine level is too much higher than 5. Different people have different conditions, just likes the physical quality of two persons is different. Then when is dialysis necessary?

When the high creatinine begins to cause some symptoms, like nausea, vomiting, somnolence, heart problems and so on, dialysis must be used to help them eliminate the waste products and excessive water. However, dialysis does lower creatinine obviously and the excessive water, as to the aspect that repairing the damaged kidney inherent cells and recovering kidney function, dialysis does nothing. Moreover, the final result of dialysis must be a kidney function, Renal Failure patients are eager to avoid or get rid of dialysis. For Renal Failure Patients, Dialysis Is Not A Long Plan for The Future.

The clinical experience has been showed that Chinese herbal medicines can enhance the kidney function, you could never imagine how excited they are when patients see they can pass urine again. As long as the kidney function can be enhanced to about 20%, dialysis is likely to be stopped. More kidney function is left, better the prognosis will be.