Why does IgA Nephropathy always relapse

IgA Nephropathy can occur at any age, even in childhood. It affects more men than women. IgA Nephropathy is one of the most common diseases of the kidney, other than those caused by Diabetes or high blood pressure. For patients with IgA Nephropathy, the most troublesome problem is the relapse. Then why does IgA Nephropathy always relapse?
How does IgA Nephropathy happen?
When people’s immune system becomes abnormal, their immunity will be low. The virus or bacteria will invade the human body, at this time, the human body will produce the abnormal IgA which will combine with antigen and then produce immune complexes. Being the immune system is abnormal, these immune complexes will deposit in the kidneys. These immune complexes don’t belong to kidneys, and kidneys will treat them as the foreign body, so immune inflammation reaction happens. But the immune inflammation reaction can also damage kidneys, and the damage is more severe than that caused by immune complexes.
Why does IgA Nephropathy relapse?
In clinical, patients with IgA Nephropathy usually are treated with medicines. Symptom like proteinuria will be treated by the steroid drugs, the immunosuppressive drugs will be used to restrain the immune inflammation reaction to stop the further damage to kidneys. However, only medicines is not enough. From the information above, we know that the immune complexes depositing in kidneys still exist, and there are no western medicine can eliminate them, which means the immune inflammation reaction may reappear at ant time. At this time, if patients have any infections, even a cold, IgA Nephropathy will happen again.
If we want to treat IgA Nephropathy from the root, we must restore the innate immune system of human body. In that case, even though there are infections, our immune system will eliminate them and there has no immune complexes deposit in kidneys, then no immune inflammation reaction, then no kidney damage. Also the kidney damage should be repaired. Immunotherapy brings hopes for IgA Nephropathy patients, as to how Immunotherapy works to treat IgA Nephropathy, patients can ask the online experts or leave us a message. Don’t forget that you are not alone, we will be there fighting against the disease with you.