Because of the effects of the glomerulus menbrane filtration and the renal
tubular reabsorption,the protein(almost means the smaller molecular weight
protein) content in healthy people’ urine is very little(excrete volume is less
than 150mg every day),the protein qualitative check is negative reaction.When
the protein content in the urine goes up,the ordinary urine routine test will
check out proteins,and this is called proteinuria.If the protein content is
equal or greater than 3.5g/24h,it is called heave proteinuria.
Proteinuria is a representative symptom of chronic kidney disease,the reasons
for the formation of proteinuria are intimate on the glomerular barrier
functions.Glomerular capillary is made up with three structures,
inside-to-outside,there are endodermis cell layer,base film layer and epithelial
layer.The three cell layers distribute unequal size filtration pores and
negative charges,so the glomerular barrier function can be divided into two
kinds: mechanical barrier ---filtration pores and electrostatic
barrier----negative charges.
When the kidney is pathology,a series of changes will happen to the
glomerular basement membrane(GBM):its filtration pores enlarging or closing、GMB
fracturing,electrostatic barrier injuring,kidney permeability
enhancing,negatively charged glycoprotein reducing or disappearing in filtration
membrane,all of these will cause the negatively charged plasma proteins’
filtration rate to increase more obviously than it is as usual.So,at this moment
it forms proteinuria clinically.
Would like to kmow more about Micro-Chinese Medicine Osmotherapy: Natural Proteinuria Treatment for FSGS Patients? Welcomed to contact our online doctor,
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