The symptoms of PKD

● Backache
it often have tension in the small of back or dull pain, sometimes sharp pain. That can aggravate due to physical activity or walking time is too much, but can release by laying in bed. Bleeding in kidney, stone movement or infection are also the reasons causing sharp pain suddenly.
● Blood in urine
About 50% of patients have microscopic hematuria, and can also have paroxysmal gross hematuria, which is caused by the angiorrhexis of cyst wall. When bleeding much and the blood clot passes ureter, colica will happen. Blood in urine is often accompanied by leucocyturia and proteinuria, and in general, the volume of urine protein doesn't exceed 1.0g/d. When some infections happen in the kidney, pyuria will become obvious and blood in urine becomes more severe.
● High blood pressure
Before the creatinine level increases, about one half of patients get high blood pressure. That is because these cysts oppress the surrounding tissues and the renin, angiotensin are activated. High blood pressure can make the cysts grow faster and speed up the development of condition, which influences the prognosis directly.
● Kidney swelling
The development of pathological changes in two sides kidneys is not symmetrical, the sizes are different. And to the late stage, two kidneys can fill the whole enterocoelia, kidney surface has lots of hydatoncus, which makes the shape of kidney is not regular, is sagsandcrests.